The wealth of information derived from decades of fundamental biology research is now being augmented weekly by massive amounts of data from new genomic technologies. In a single experiment, researchers can determine the activity levels for all of the roughly 25,000 human genes from hundreds of tumors. These data are generating new tests to more accurately diagnose cancer and new, more effective treatments with minimal side effects. Searching through this ocean of data for those valuable prizes would be impossible without today's powerful information technology.
In this edition of Quest, you will read about the generous gift from Bob and Pat Herbold to support the Hutchinson Center's new program in computational biology and bioinformatics. These highly specialized fields use cutting-edge computer technology to blend the disciplines of biology, mathematics and statistics to boost the speed, productivity and cost-effectiveness of cancer-research studies. In short, this work will greatly accelerate the pace of lifesaving discoveries.
The Herbolds' $1.5 million gift will help us build one of the best computational biology programs in the world and firmly establish Seattle as a center of excellence in the field. It will hasten development of the program's infrastructure and allow us to attract the best minds in these disciplines.
Their gift also underscores the importance of private donations to the Hutchinson Center. Every private gift plays an essential role in hiring top researchers, keeping pace with technology, and improving cancer prevention, early detection and treatment. In fact, your donations supported the recruitment of Dr. Robert Gentleman, a world leader in the field, to direct our computational biology program.
You will also read about two other newly recruited scientists, also supported by private donations: Drs. Marc Van Gilst and John Pagel. Marc is the newest faculty member in our renowned Basic Sciences Division. His groundbreaking research is providing insight into the molecules that regulate the body's metabolic pathways. In turn, his discoveries may ultimately lead to therapies for diabetes, obesity and cancer.
John Pagel, one of the newest physician/researchers in our Clinical Research Division, is building upon the pioneering work of other Hutchinson Center researchers in the field of radioimmunotherapy, which delivers radiation directly to tumor sites. John is refining this therapy, aiming to make it safe and more effective for leukemia and lymphoma patients.
These stories are just a few examples of how private gifts make the Hutchinson Center's vital work possible. Thanks to the support of our community, we are celebrating our 30th year of medical advances for patients with cancer, HIV and other life-threatening diseases. Together, we're pushing the boundaries of lifesaving knowledge.
Dr. Lee Hartwell
President and Director