Human Biology Division

Labs

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Division labs »

Center labs and projects »

  • Alanna Ruddell
    Human Biology
  • Bolouri Lab
    Human Biology
    The Bolouri Lab is interested in understanding how gene regulatory interactions control cellular state and identity, particularly during development (e.g. in stem cells). The lab specializes in the development and use of computational systems biology methods to map gene regulatory networks.
  • Emerman Lab
    Human Biology, Basic Sciences
    The Emerman Lab studies the molecular and evolutionary basis for the replication of HIV and related viruses, with an emphasis on the interaction of these viruses with their host cells. Their goal is to understand what determines resistance or vulnerability to current, past and potential viral diseases.
  • Galloway Lab
    Human Biology
    The Galloway Lab studies the mechanisms by which human papillomaviruses contribute to cancer, with an emphasis on types most likely to progress to cervical cancer. They work to understand the natural history of genital HPV infections and why only a small subset of women infected with high-risk HPVs develop cancer.
  • Geballe Lab
    Human Biology
    The Geballe Lab studies the functions and mechanisms of genes encoded by large DNA viruses, such as cytomegalovirus and vaccinia virus, that act to promote viral growth by blocking host cell defenses.
  • Grandori Lab
    Human Biology
    The Grandori Lab focuses on exploiting the weaknesses of cancer cells to identify targeted, less toxic cancer therapies. RNA interference (RNAi) combined with high throughput technology enables us to interrogate the human genome for genes that are essential for viability of molecularly defined cancer cells, thus allowing the unbiased identification of these Achilles' heels.
  • Kemp Lab
    Human Biology
    The Kemp Lab studies tumor formation in mice to better understand how environmental and genetic factors interact to cause cancer. They also work to develop simple blood tests for early cancer detection by discovering biomarkers, the proteins that signal the earliest traces of disease.
  • MacPherson Lab
    Human Biology
  • Miller Lab
    Human Biology, Basic Sciences
    The Miller Lab studies the basic biology of viral gene transfer. Their goals include developing gene-therapy treatments for lung diseases and generating induced pluripotent stem cells, which are useful for cell therapy in humans. Another major focus has been the jaagsiekte sheep retrovirus, which may provide insight into human lung cancer.
  • Overbaugh Lab
    Human Biology
  • Paddison Lab
    Human Biology
    The Paddison Lab uses functional genetics to probe the underlying biology of mammalian stem/progenitor cells. We identify and characterize gene products affecting stem cell self-renewal, differentiation, proliferation, or survival through the use of RNAi knockdown technologies.
  • Paddison Lab
    Human Biology
  • Peichel Lab
    Human Biology
    The Peichel Lab uses a small fish called the threespine stickleback as a model organism to conduct research aimed at identifying the genetic and molecular mechanisms that underlie evolutionary processes. Research topics include understanding evolution of the fish's behavior and sex chromosomes.
  • Peter Nelson Lab
    Human Biology
    Dr. Peter Nelson's lab focuses on understanding the molecular, cellular and physiological events that lead to cancer initiation and progression. A particular emphasis involves hormonal carcinogenesis and prostate cancer with the goal of developing new strategies for diagnosis, prognosis and therapy.
  • Porter Lab
    Human Biology
    The Porter Lab focuses on identifying and understanding the molecular events in normal and cancer cells that are associated with the initiation and progression of human cancer, with a focus on breast and ano-genital cancers. They also investigate the molecular profiles that distinguish different types of cancer or determine an individual's cancer risk.
  • Reid Lab
    Human Biology
  • Salama Lab
    Human Biology
  • Taniguchi Lab
    Human Biology
    The Taniguchi Lab's long-term research objective is to elucidate molecular mechanism of DNA damage response pathways, such as the Fanconi Anemia-BRCA (FA-BRCA) pathway, and their involvement in carcinogenesis.
  • Tapscott Lab
    Human Biology
    The Tapscott Lab studies gene transcription and expression in normal development and disease, with an additional emphasis on rhabdomysarcomas (cancers with characteristics of skeletal muscle) and human muscular dystrophies. Other research areas include gene and cell therapies for muscular dystrophy, and the biology of triplet repeats and their associated diseases.
  • Tewari Lab
    Human Biology
    The Tewari Lab draws on perspectives from systems biology and complexity science to address important problems in basic and applied cancer research. More specifically, the lab is investigating microRNAs, which are 22 nt non-protein-encoding RNA molecules that function to repress messenger RNA targets to modulate gene expression networks.
  • Transmission of Stomach Bacteria Study
    Human Biology
    Fred Hutchinson Cancer Research Center is recruiting families to participate in a study about the transmission of Helicobacter pylori, a stomach bacteria infecting half of the world's population. The bacteria can cause ulcers and stomach cancer.
  • Vasioukhin Lab
    Human Biology
    The Vasioukhin Lab works to better understand how individual cells work together to produce and maintain a normal mammalian organism. The underlying idea is that cancer can occur as a result of breakdowns in the mechanisms that regulate this communication.
Fred Hutchinson Cancer Research Center is a world leader in research to prevent, detect and treat cancer and other life-threatening diseases.