Cancer Prevention Program

Women’s Health Initiative Sequencing Project (WHISP)

WHISP is part of the National Heart, Lung, and Blood Institute’s (NHLBI), Grand Opportunity Exome Sequencing Project (ESP). This is a program aiming to discover novel genes and mechanisms contributing to heart, lung and blood disorders, using next generation sequencing technology.  The primary focus is on the discovery of novel rare variants through sequencing the exome of several thousand subjects selected for early onset myocardial infarct, stroke, extreme obesity, blood pressure, lipids, and other related traits and lung diseases.  Subsequent follow-up studies include ExomeChip genotyping and candidate gene sequencing to identify novel susceptibility loci.  ESP includes several well characterized studies across the United States with over 200,000 participants. Drs. Carlson, Peters and Kooperberg are co-leading the WHISP efforts at the coordinating center of the Women’s Health Initiative. More information can be found here: https://esp.gs.washington.edu/drupal/

For questions or additional information please contact:

Chris Carlson, PhD
Associate Member
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue N
M4-B402
PO Box 19024
Seattle, WA 98109-1024
Phone: (206) 667 7850
Email: ccarlson@fhcrc.org

Ulrike (Riki) Peters, PhD, MPH
Associate Member
Fred Hutchinson Cancer Research Center
Research Associate Prof University of Washington
1100 Fairview Avenue N
M4-B402
PO Box 19024
Seattle, WA 98109-1024
Phone: (206) 667-2450
Email: upeters@fhcrc.org

Or

Charles Kooperberg, PhD
Full Member
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue N
M3-A410
PO Box 19024
Seattle, WA 98109-1024
Phone: (206) 667 4142
Email: clk@fhcrc.org

Fred Hutchinson Cancer Research Center is a world leader in research to prevent, detect and treat cancer and other life-threatening diseases.