David Fredricks, MD Associate Member Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center Associate Professor Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington

Dr. Fredricks’ research is focused on improving the diagnosis of infectious diseases through the application of molecular methods such as the polymerase chain reaction (PCR) and fluorescence in situ hybridization (FISH). The Fredricks lab collaborates with other investigators at the Center to identify bacterial and fungal infections in immunocompromised patients, such as persons receiving treatment for cancer or undergoing hematopoietic cell transplantation.

Dr. Fredricks also studies uncultivated microbes, the constituents of the human microbial flora, and the role of bacterial communities in human disease.   In particular, he is studying the role of uncultivated bacterial communities in the syndrome bacterial vaginosis. The lab also uses nucleic acid sequences to detect and identify novel microbes in other poorly understood human diseases.   The following are projects in which Dr. Fredricks is currently involved.

• Quantitative PCR for the Diagnosis of Fungal Infections
• Molecular Microbiology of Human-Associated Niches and Novel Pathogen Discovery
• Adult Leukemia Center Grant: Microbiology Core

Community of Science webpage:

http://myprofile.cos.com/DFredricks