Research Initiatives:
1. A. fumigatus antifungal drug resistance. Antifungal drug resistance is an under-appreciated problem in Aspergillus species. We have recently identified an azole-resistant variant, which we call A. fumigatus v. lentulus. Future multi-site studies are being developed to determine the importance of this isolate and to develop rapid antifungal susceptibility testing methods for moulds.
Publications
Balajee SA and Marr KA . A conidial viability assay for rapid susceptibility testing of Aspergillus species . J Clin Microbiol 40(8):2741-5 (2002).