Research Activities in ID

• CMV Infection in Hematopoietic Stem Cell Transplant Recipients: Michael Boeckh, MD
• HSV Infection in Hematopoietic Stem Cell Transplant Recipients: Anna Wald#, MD, MPH
• HSV Infection in HIV Infected Individuals: Lawrence Corey, MD
• Cytotoxic T-Cell Responses to HSV in HIV-Infected Persons:  Christine Posavad, PhD
• Transmission and Acquisition of Human Herpes Virus 8: Lawrence Corey, MD; Jeff Vieira, PhD; Meei-Li Huang, PhD
• Immune Correlates of HSV-2 Disease Severity: David Koelle, MD #

• To Characterize Immune Responses to Aspergillus fumigatus: Kieren Marr, MD
• Antifungal Drug Resistance to Moulds: Kieren Marr, MD
• To Develop Strategies to Prevent Aspergillous: Kieren Marr, MD
• Quantitative PCR for the Diagnosis of Fungal Infections:  David Fredricks, MD

• Clinical Epidemiology and Pathogenesis of Asymptomatic HSV Program Project: Lawrence Corey, MD, Principal Investigator
  • Prevention of HSV Morbidity in Pregnancy and in Newborns: Zane Brown+, MD
  • Biology and Epidemiology of Genital HSV Acquisition: Anna Wald#, MD, MPH
  • Virology Research Clinic (VRC): Anna Wald+, MD, MPH
  • Local Immune Responses to HSV Specific Proteins: Rhoda (Ashley) Morrow, PhD
• Phase I Trial of HSC 70-gB2 442-451 for Herpes Simplex Virus Infection: David Koelle, MD #
• Herpes Simplex Inhibition of CTL-Induced Apoptosis: Keith Jerome, MD, PhD
• Control of Lymphocyte Trafficking in HSV Infection :  David Koelle, MD #

Research in HIV Infection

• Immunology and Molecular Virology of Acute HIV Infection: Lawrence Corey, MD; M. Juliana McElrath, MD, PhD
• HIV Vaccine Trials Unit (HVTU): M. Juliana McElrath, MD, PhD
• Mucosal Cellular Immunity in HIV Infection: M. Juliana McElrath, MD, PhD
• Immunology of Primary HIV-1 Infection: M. Juliana McElrath, MD, PhD
• Acquired Mucosal Antibodies to HIV: Rhoda Ashley Morrow, PhD +
• Protection against HIV-1 Infection in Exposed Seronegatives: M. Juliana McElrath, MD, PhD
• Slow disease progression in HIV-1 and HIV-2 infection: M. Juliana McElrath, MD, PhD
• Vaccine Immunogenicity:  M. Juliana McElrath, MD, PhD
• HIV Shedding in Semen - Causes and Genitourinary Tract Consequences: Robert Coombs+, MD, PhD
• Clinical Retrovirology and Virology Core Laboratories: Robert Coombs+, MD, PhD
• Reconstitution of CMV Immunity in HIV-Infected Hosts: Michael Boeckh, MD; Stanley Riddell*, MD
• Lesion T-Cell Response to HSV in HIV Infection: David Koelle, MD #
• Suppressing HIV-1 Infection in Exposed Seronegative Adults:   Tuofu Zhu, MD+
• Minimal Levels of HIV-1 Infection Tuofu Zhu, MD+
• Human Genes and Related Polymorphysims that Affect HIV Infection and Disease Progression, Tuofu Zhu, MD+
• Roles of Monocytes/Macrophages in HIV-1 Infection   Tuofu Zhu, MD+ 
• Control of SIV Infection at Extremely Low Levels in vivo Tuofu Zhu, MD+

Hepatitis Research

• Hepatitis C Virus (HCV) Pathogenesis in Liver Transplant Recipients: David Gretch+, MD, PhD
• Clinical Virology of Hepatitis C (Molecular Virology Core Laboratory): David Gretch+, MD, PhD
• Viral Hepatitis Diagnostic Laboratory: David Gretch+, MD, PhD
• Hepatitis Therapeutics: David Gretch+, MD, PhD
• Hepatitis C Induced Interleukin 8 and Inhibition of Interferon Steve Polyak, Ph.D +
• HCV-Host Interactions and Ethanol; Steve Polyak, Ph.D+
• Mechanisms of Resistance to Antiviral Therapy by Hepatitis C Virus (HCV): Steve Polyak+, PhD

• Epidemiology of Infection after Blood and Marrow Transplantation (BMT): Michael Boeckh, MD
• Molecular Diagnostic Laboratory: Lawrence Corey, MD; Meei-Li Huang, PhD; Keith Jerome, MD, PhD
• Adult Leukemia Research Center - Infectious Disease Core Laboratory: Lawrence Corey, MD; Michael Boeckh, MD
• Center for AIDS Research - Clinical Research Center: Lawrence Corey, MD
• Virology Laboratory Core: Rhoda Ashley Morrow+, PhD
• Viral Diagnostic Laboratory: Lawrence Corey, MD; Rhoda Ashley Morrow, PhD+
• Respiratory Syncytial Virus (RSV) Study: Michael Boeckh, MD;

• Molecular Microbiology of Human-Associated Niches :  David Fredricks, MD
• Pathogen Discovery and Identification: The Role of Novel Microbes in Unexplained Diseases : David Fredricks, MD
• Granulocyte Transfusions for Severe Infections after HSCT : Michael Boeckh, MD

* designates interdisciplinary research conducted with FHCRC scientists
+designates research with UW Virology Division scientists

#designates research conducted with an affiliated FHCRC scientist