Clinical Research Chemotherapy

Chemicals used for chemotherapy generally seem to inhibit cell division and lead to cell death. Cancer cells, which are actively dividing, are affected by these drugs but other dividing cells in the body are affected as well. Chemotherapeutic drugs have a greater effect on cancer cells than on normal cells, but it is not entirely understood why this is true.

Chemotherapeutic agents

Classes Examples
Antimetabolites 6-mercaptopurine
Alkylating agents Cyclophosphamide
Anthracyclines Mitoxantrone
Topoisomerase inhibitors Camptothecan,Taxol


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