New Approaches to Cancer Therapy
The following new approaches, all in clinical trials, have been developed based on our increased understanding of the molecular and cellular bases of cancer and the progression of the disease.
- Antimetastasis: block the spread of cancer cells and the invasion
of new tissues.
- Antiangiogensis: block development of blood vessels that nourish
a tumor.
- Antisense oligonucleotides: block production of aberrant proteins
that cause proliferation of tumor cells.
- Gene therapy: introduce genes into T cells that are injected into
the patient and are designed to kill specific tumor cells.
- p53: introduce normal p53 genes into mutant cancer cells to re-establish sensitivity to chemotherapeutic drugs
