Papers from the Biggins Lab

S. Furuyama & S. Biggins
Centromere identity is specified by a single centromeric nucleosome in budding yeast. 2007. 104(37) 14706-14711.
& S. Biggins
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C. V. Kotwaliwale, S. Buvelot Frei, B.M. Stern & S. Biggins
A pathway containing the Ipl1/Aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly. 2007. Dev Cell.13(3) 433-445.
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K. A. Collins, R. Camahort, C. Seidel, J.L. Gerton & S. Biggins
The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation. 2007. Genetics.175: 513–552.
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C. V. Kotwaliwale & S. Biggins
Microtubule capture: A concerted effort. 2006. Cell.127 1105-1108.
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C. Norden, M. Mendoza, J. Dobbelaere, C. V. Kotwaliwale, S. Biggins & Y. Barral
The NoCut pathway links abscission to proper function of the spindle midzone and prevents chromosome breakage by the cytokinetici machinery. 2006. Cell.125 (1) 85-98.
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B. A. Pinsky, C. V. Kotwaliwale, S. Y. Tatsutani, C. A. Breed & S. Biggins
Glc7/Protein Phosphatase-1 Regulatory Subunits can oppose the Ipl1/Aurora Protein kinase by redistributing Glc7. 2006. Mol. Cell Biol.(7) 2648-60
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B. A. Pinsky, C. Kung, K. M. Shokat & S. Biggins
The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores. 2006. Nat. Cell Bio. 8: 78-83.
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K. Collins, A. Castillo, S. Tatsutani & S. Biggins
De novo kinetochore assembly requires the yeast centromeric histone H3 variant. 2005. Mol Biol. Cell. 16: 5649-5660.
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B. Pinsky & S. Biggins
The spindle checkpoint: tension versus attachment 2005. Trend Cell Biol. 15: 486-493.
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R. Kamakaka & S. Biggins
Histone variants: deviants? 2005. Genes Dev. 19: 295-316.
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K. A. Collins, S. Furuyama & S. Biggins
Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. 2004. Curr Biol. Nov 9;14(21):1968-72.
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S. Biggins
Correcting SYNful attachments. 2004. Nat Cell Biol Mar;6(3):181-3.
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B. A. Pinsky, S. Y. Tatsutani, K. A.Collins & S. Biggins
An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. 2003. Dev Cell Nov;5(5):735-45.
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S. Biggins & C.E. Walczak
Captivating capture:how microtubules attach to kinetochores. 2003. Curr Bio May 27;13(11):R449-60.
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S. Buvelot, S. Y. Tatsutani, D. Vermaak & S. Biggins
The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. 2003. J Cell Biol. Feb 3;160(3):329-39.
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B.A. Pinsky & S. Biggins
Top-SUMO wrestles centromeric cohesion. 2002. Dev Cell. Jul;3(1):4-6. Review.
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N. Bhalla, S. Biggins & A.W. Murray
YCS4,a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. 2002. Mol Biol Cell. Feb;13(2):632-45.
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S. Biggins & A.W. Murray
The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. 2001. Genes Dev. Dec 1;15(23):3118-29.
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S. Biggins, N. Bhalla, A. Chang, D. Smith & A.W. Murray
Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. 2001. Genetics Oct;159(2):453-70.
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S. Biggins, F. F. Severin, N. Bhalla, I. Sassoon, A.A.Hyman & A.W. Murray
The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Genes Dev. 1999 Mar 1;13(5):532-44.
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S. Biggins & A.W. Murray
Sister chromatid cohesion in mitosis. 1998. Curr Opin Cell Biol. Dec;10(6):769-75. Review.
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