Olson Lab Publications
- Fan W, Pritchard JI, Olson JM, Khalid N, Zhao LP. A class of models for analyzing GeneChip gene expression analysis array data. BMC Genomics 6(1):16, 2005.
Abstract
- Strand AD, Aragaki AK, Shaw D, Bird T, Holton J, Turner C, Tapscott SJ, Tabrizi SJ, Schapira AH, Kooperberg C, Olson JM. Gene expression in Huntington's disease skeletal muscle: a potential biomarker.
Hum Mol Genet 14(13): 1863-1876, 2005. Full Text Abstract
- Hallahan AR, Pritchard JI, Hansen S, Benson M, Stoeck J, Hatton BA, Russell TL, Ellenbogen RG, Bernstein ID, Beachy PA, Olson JM. The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas.
Cancer Res 64(21):7794-800, 2004. Abstract
- Olson JM and Hallahan AR. p38 MAP kinase: a convergence point in cancer therapy. Trends Mol Med 10(3): 125-129, Mar 2004. Abstract
- Lin C-H, Stoeck J, Ravanpay AC, Guillemot F, Tapscott SJ, Olson JM. Regulation of neuroD2 expression in mouse brain. Dev Biol 265: 234-245, 2004. Abstract
- Hallahan AR, Pritchard JI, Chandraratna RA, Ellenbogen RG, Geyer JR, Overland RP, Strand AD, Tapscott SJ, Olson JM. BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect. Nature Med 9(8):1033-8, August 2003. Abstract
- Ditzler S, Stoeck J, LeBlanc M, Kooperberg C, Hansen S, Coppin L, Olson JM. A Rapid Neurobehavioral Assessment Reveals that FK506 Delays Symptom Onset in R6/2 Huntington's Disease Mice.
Preclinica. 1(3): 115-126, July/August 2003. Abstract
- Strand AD, Olson JM, Kooperberg C. Estimating the statistical significance of gene expression changes
observed with oligonucleotide arrays. Hum Mol Genet 11(19): 2207-21, Sep 2002. Abstract
- Berman DM, Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, Beachy PA. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science. 297(5586): 1559-61, Aug 2002. Abstract
- Xu XL, Olson JM, Zhao LP. A regression-based method to identify differentially expressed genes in
microarray time course studies and its application in an inducible
Huntington's disease transgenic model. Hum Mol Genet 11(17): 1977-85, Aug 2002. Abstract
- Lieberman AP, Harmison G, Strand AD, Olson JM, Fischbeck KH. Altered transcriptional regulation in cells expressing the expanded
polyglutamine androgen receptor. Hum Mol Genet 11(17): 1967-76, Aug 2002. Abstract
- Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E. Early transcriptional profiles in huntingtin-inducible striatal cells by
microarray analyses. Hum Mol Genet 11(17): 1953-65, Aug 2002. Abstract
- Luthi-Carter R, Strand AD, Hanson SA, Kooperberg C, Schilling G, La Spada AR, Merry DE, Young AB, Ross CA, Borchelt DR, Olson JM. Polyglutamine and transcription: gene expression changes shared by DRPLA
and Huntington's disease mouse models reveal context-independent
effects. Hum Mol Genet 11(17): 1927-37, Aug 2002. Abstract
- Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, Peters NL, Woods AM, Chan EY, Kooperberg C, Krainc D, Young AB, Tapscott SJ, Olson JM. Dysregulation of gene expression in the R6/2 model of polyglutamine
disease: parallel changes in muscle and brain. Hum Mol Genet 11(17): 1911-26, Aug 2002. Abstract
- Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM. Increased huntingtin protein length reduces the number of
polyglutamine-induced gene expression changes in mouse models of
Huntington's disease. Hum Mol Genet 11(17): 1939-51, Aug 2002. Abstract
- Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME,
Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran
T, Wetmore C, Biegel JA, Poggio T, Mukherjee S, Rifkin R, Califano A, Stolovitzky
G, Louis DN, Mesirov JP, Lander ES, Golub TR. Prediction of central nervous
system embryonal tumour outcome based on gene expression. Nature, Jan 24;415(6870):436-42,
2002. Abstract
- Hughes RE, Lo RS, Davis C, Strand AD, Neal CL, Olson JM, Fields S. Altered
transcription in yeast expressing expanded polyglutamine. Proc Natl Acad Sci
U S A. Nov 6;98(23):13201-6, 2001. Abstract
- Thomas JG, Olson JM, Tapscott SJ, Zhao LP. An efficient and robust statistical
modeling approach to discover differentially expressed genes using genomic
expression profiles. Genome Res. Jul;11(7):1227-36, 2001. Abstract
- Olson JM, Asakura A, Snider L, Hawkes R, Strand A, Stoeck J, Hallahan A,
Pritchard J, Tapscott SJ. NeuroD2 is necessary for development and survival
of central nervous system neurons. Dev Biol 234(1): 174-87,
2001. Abstract
- Thomas JG, Olson JM, Tapscott SJ, Zhao LP. An efficient and robust statistical
modeling approach to discover differentially expressed genes using genomic
expression profiles. Genome Res 11(7): 1227-36, Jul 2001. Abstract
- Hughes RE, Olson JM. Therapeutic opportunities in polyglutamine disease.
Nature Med 7(4): 419-23, Apr 2001. Abstract
- Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon
AS, Frey AS, Spektor BS, Penney EB, Schilling G, Ross CA, Borchelt DR, Tapscott
SJ, Young AB, Cha JH, Olson JM. Decreased expression of striatal signaling
genes in a mouse model of Huntington's disease. Hum Mol Genet
9(9): 1259-71, 2000. Abstract
- Farah MH, Olson JM, Sucic HB, Hume RI, Tapscott SJ, Turner DL. Generation
of neurons by transient expression of neural bHLH proteins in mammalian cells.
Development 127(4): 693-702, Feb 2000. Abstract
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