Chris Bond
(Graduate Student, 1995 - 2000)
Division of Basic Sciences
Program in Structural Biology
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N.
Seattle, WA 98109
and
Graduate Program in Biomolecular Structure and Design
University of Washington
Seattle, WA
Current Contact Information:
Research Scientist, Catalyst Bioscience
cbond@catbio.com
650-266-8660
1. Bond, C., Jurica, M. S., Mesecar, A. and Stoddard, B. L.
(2000) "Determinants of
allosteric
activation of yeast pyruvate kinase and identification of novel
effectors using computational screening " Biochemistry 39:
15333 - 15343 .
2. Bond, C. J., Huang, J. -Y., Hajduk, R., Heath, P. J.,
Flick, K. E., and Stoddard, B. L. (2000) "Cloning, sequence and
crystallographic
structure of recombinant iron superoxide dismutase from
Pseudomonas
ovalis" Acta Cryst D56
1359 - 1366.
Plus publications from his graduate
work in the Daggett Lab in the UW BMSD program:
3. Clarke J, Hounslow AM, Bond CJ,
Fersht AR, Daggett V. The effects of disulfide bonds on
the denatured state of barnase. Protein
Sci. 2000 9(12): 2394-404.
4. Wong KB, Clarke J, Bond CJ, Neira
JL, Freund SM, Fersht AR, Daggett V. Towards a complete
description of the structural and dynamic properties of the denatured
state of barnase and the role of residual structure in folding. J Mol Biol. 2000 Mar 10 296(5):
1257-82.
5. Bond CJ, Wong KB, Clarke J, Fersht
AR, Daggett V. Characterization of residual structure in the
thermally denatured state of barnase by simulation and experiment:
description of the folding pathway. Proc Natl Acad Sci U S A. 1997
94(25): 13409-13.
Plus publications from his
postdoctoral time at Genentech:
6. Bond CJ, Wiesmann C, Marsters JC
Jr, Sidhu SS. A structure-based database of antibody variable
domain diversity. J Mol Biol.
2005 348(3): 699-709.
7. Kotz JD, Bond CJ, Cochran AG.
Phage-display as a tool for quantifying protein stability determinants.
Eur J Biochem. 2004 271(9):
1623-9.
8. Bond CJ, Marsters JC, Sidhu SS. Contributions
of CDR3 to VHH domain stability and the design of monobody scaffolds
for naive antibody libraries. J Mol
Biol. 2003 332(3): 643-55.
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