More Information

Where does the CARB Study take place?

All study activities will take place at the Hutchinson Center's Prevention Center. The Prevention Center includes the clinic and also the Human Nutrition Lab dining room where you will eat your meals and pick up your food to take home. The Prevention Center is located on the E Level of the Robert Arnold Building on Fred Hutchinson Cancer Research Center — Day Campus (Fairview Ave. N and Campus Drive) in Seattle. Parking is free in the Arnold Building garage, entered from Campus Drive, and open from 7:00 a.m. to 7:00 p.m.

Metro Bus Routes serving The Hutchinson Center are the #66 (Eastlake Ave. N and Aloha) and the #70 (Fairview Ave. N and Yale), and the South Lake Union Streetcar.

Free shuttle bus service to FHCRC is available Monday through Friday from the University of Washington Health Science Building, D wing.

Click here for map: www.fhcrc.org/about/visitor/parking/fhcrcvisitormap.pdf

You cannot do the following while on the study:

If you are prescribed any medication or if you must take an over-the-counter medication, dietary or herbal supplement during the study, please let us know. We may need to ask you to withdraw or change your study dates.

We also ask you not to start any new exercise programs while you are in the study. Please continue your usual physical activities.

If you are female and you become pregnant or decide to try to get pregnant while you are in the study, we will ask that you withdraw from the study.

What are the Benefits of the Study?
You will benefit from this study by receiving a nutrient analysis of your usual food intake and the results of the DEXA scan at the end of the study. You will also be helping us in our research on cancer prevention. This research may benefit society in the future by developing recommendations about diets that may prevent cancer.

What Are The Risks of the Study?
Blood draw: You may experience a little discomfort or have a temporary bruise from having blood drawn. Occasionally you may feel lightheaded or feel faint when having blood drawn. If you feel faint, tell the person drawing your blood and she or he will have you lie down until the feeling goes away. Sugar-containing drinks will also be available.

DEXA scan: The DEXA scan involves exposure to radiation. Although it can vary from person to person, the whole-body radiation exposure from each DEXA scan will be about 5 mrem. The total exposure for the study will be about 2% of the average annual exposure a person in the United States receives from natural background radiation. The risk of harm from this amount of radiation is low and no harmful health effects are expected; however, the risk of harmful effects may increase if a person is exposed to more procedures that involve radiation.

Diet: You may have mild bloating or abdominal discomfort for a few days at the beginning of each diet period. This is because the study diet may be higher in fiber than your usual diet.

Urine and stool collections: Collecting urine and stool samples may cause you to feel uncomfortable.

What Will We Do With Your Samples?
Blood: We will look at some substances normally made by your body, including glucose, insulin, leptin, proteins and associated components.
Urine: We will measure breakdown products of the diet.
Stool: We will look at the types of bacteria present in your stool.

Compensation

After you complete the entire study, you will receive $750. Because of the study's design, you must complete both feeding periods before receiving payment. If you are unable to complete the study (due to illness, family emergency, unforeseen circumstances), but you have completed one feeding period, you will receive $250. If you do not complete any feeding period, no payment can be given.

You will receive an additional compensation of $20 for each stool sample collection, and $200 for completing both Postprandial Tests.


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