Use of Exogenous Progestins and Risk of in situ and Invasive Breast Cancer

PI: Christopher Li PhD

This study involves two projects. The first project investigates the relationship between use of depo-medroxyprogesterone acetate on risk of in situ breast cancer among premenopausal women 20-44 years of age. The second study is a population-based case-control study evaluating the relationship between use of progestin containing hormone therapy regimens and risk of invasive pure lobular, ductal/lobular, and ductal carcinomas among postmenopausal women 55-74 years of age. This study will also assess the epidemiologic, pathologic, and molecular differences between these three histologic types of breast cancer.