Seattle Cancer and Aging Program

Year 1 Pilot Projects

Daniel Gottschling
Genomic instability in old yeast: A model for the link between cancer and age

Peter Rabinovitch and Bradley Preston
Age, telomere shortening and the risk of gastrointestinal cancer

Derek Stirewalt and Eric Larson
Surrogate markers of cancer susceptibility in older patients

Jim Roberts
A possible new function for telomerase in tumorigenesis

Joachim Deeg and Norm Wolf
Aging and myelodysplasia

Monique Cherrier and Mary Ersek
Neurocognitive effects of opioids in older adults

Raymond Monnat and Michael MacCoss
Identification and quantitation of Fanconi and Werner Syndrome proteins.

Year 2 Pilot Projects

May Reed and Stephen Plymate
Prostate Cancer and Angiogenesis in Aging

Peter Nelson and Stephen Plymate
Identification and characterization of aging- and senescence-associated paracrine factors mediating prostate carcinogenesis.

Anne McTiernan and Janet Stanford
Effect of Exercise on Prostate Cancer Biomarkers: An Ancillary Study to a Randomized Controlled Clinical Trial

Year 4 Pilot Projects (New)

Michael Linenberger
Donor Safety and Apheresis Collection Parameters in Elderly, Related Allogeneic Peripheral Blood Stem Cell Donors

Junko Oshima
Mitochondrial Genetic Instability, Cancer and Aging

Sam R. Sharar
A Pilot Study of Virtual Reality Analgesia for Cancer Pain in the Elderly

Julia M. Sidorova
Analysis of Genetic and Environmental Factors in Somatic Cell Replication Using a Single Molecule DNA Replication Asay


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