Marie Bleakley, MD, PhD, M.Msc

Assistant Member, Program in Immunology
Clinical Research Division
Assistant Professor of Pediatrics, School of Medicine
University of Washington

Education:

Flinders University of South Australia, South Australia (BMBS/MD)
The University of Newcastle, New South Wales, Australia (Master of Medical Science-Clinical Epidemiology)
The University of Sydney, New South Wales, Australia (PhD)
Residency: Pediatrics, The Children’s Hospital at Westmead, New South Wales, Australia
Fellowship:
1. Pediatric Oncology, The Children’s Hospital at Westmead, New South Wales, Australia
2. Pediatric Hematology-Oncology, Fred Hutchinson Cancer Research Center and Seattle Children’s Hospital

Research Focus:

  • Graft-versus-leukemia effect
  • Graft-versus-host disease
  • Minor histocompatibility antigens
  • Graft engineering

Clinical Expertise:

  • Pediatric leukemia
  • Pediatric allogeneic hematopoietic stem cell transplantation
  • Adoptive T cell immunotherapy to prevent and treat relapse of leukemia

Current Studies:

Clinical trials:

A Multi-center Phase II Study of Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD

A Phase II Study of Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

Laboratory studies:

Correlative laboratory studies to evaluate T cell responses in recipients of allogeneic peripheral blood stem cell grafts selectively depleted of CD45RA+ T cells

Discovery of leukemia associated minor histocompatibility antigens

Development of adoptive T cell immunotherapy targeting leukemia-associated minor histocompatibility antigens



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Contact Information

Phone
(206) 667-6572
Fax
(206) 667-7983
Email
Additional contact

Mail Stop: D3-100

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